SCHEMBL20176471

SCHEMBL20176471

c1ccc(-c2c3ccccc3c(-c3ccc(-c4ccc5c(c4)C4(c6ccccc6-c6ccncc64)c4ccccc4-5)nc3)c3ccccc23)cc1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 5/20 0.37
CYP11B1 P15538 4/20 0.34
CYP11B2 P19099 4/20 0.34
HSD17B1 P14061 1/20 0.32
HSD17B2 P37059 1/20 0.32
TNF P01375 1/20 0.32
PIK3CA P42336 1/20 0.32
FEN1 P39748 2/20 0.31
ALOX5AP P20292 1/20 0.31
MAPK10 P53779 1/20 0.31
PIK3CD O00329 1/20 0.31
HASPIN Q8TF76 1/20 0.30
HPGDS O60760 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26161151 0.99 PDK2 (0.37) PDK2CYP11B1CYP11B2HSD17B1HSD17B2
SCHEMBL26161068 0.93 PDK2 (0.42) PDK2CYP11B1CYP11B2HSD17B1HSD17B2
SCHEMBL26161250 0.92 PDK2 (0.41) PDK2HSD17B1HSD17B2TNFPIK3CA
SCHEMBL20176480 0.92 PDK2 (0.39) PDK2HSD17B1HSD17B2FEN1ALOX5AP
SCHEMBL26161291 0.91 PDK2 (0.42) PDK2CYP11B1CYP11B2HSD17B1HSD17B2
SCHEMBL26161144 0.91 PDK2 (0.39) PDK2CYP11B1CYP11B2HSD17B1HSD17B2
SCHEMBL26161337 0.88 PDK2 (0.42) PDK2CYP11B1CYP11B2HSD17B1HSD17B2
SCHEMBL26161340 0.88 PDK2 (0.42) PDK2CYP11B1CYP11B2HSD17B1HSD17B2
SCHEMBL26161147 0.87 PDK2 (0.41) PDK2CYP11B1CYP11B2HSD17B1HSD17B2
SCHEMBL20176483 0.87 PDK2 (0.41) PDK2CYP11B1CYP11B2HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2023-06-06 US disclosed
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2023-06-06 US disclosed
WO-2018093231-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME 주식회사 두산 2018-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same OR10J3, ICMT, SLCO4C1 PDK2 1916/4885CYP11B1 836/4885CYP11B2 747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.