SCHEMBL20176584

SCHEMBL20176584

c1ccc2cc3c(cc2c1)oc1ccc(-c2ccc(-c4c5ccccc5c(-c5ccncc5)c5ccccc45)cn2)cc13

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 1/20 0.36
PDGFRB P09619 1/20 0.35
PDGFRA P16234 1/20 0.35
MAPT P10636 2/20 0.34
NPC1 O15118 2/20 0.34
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
GRM4 Q14833 2/20 0.33
MAPK9 P45984 1/20 0.33
MAPK10 P53779 1/20 0.33
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
CYP1A2 P05177 3/20 0.32
CYP1A1 P04798 1/20 0.32
POLB P06746 1/20 0.32
CFTR P13569 1/20 0.32
CYP1B1 Q16678 1/20 0.32
CCNT1 O60563 1/20 0.32
CCNA2 P20248 1/20 0.32
CDK2 P24941 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17246896 0.95 PDGFRB (0.35) MAPK14PDGFRBPDGFRAMAPTNPC1
SCHEMBL26161339 0.94 PIK3CA (0.36) MAPK14PDGFRBPDGFRACYP11B1CYP11B2
SCHEMBL26161335 0.94 PIK3CA (0.36) MAPK14PDGFRBPDGFRACYP11B1CYP11B2
SCHEMBL20176698 0.92 ESR1 (0.40) MAPTNPC1CYP11B1CYP11B2GRM4
SCHEMBL26161092 0.91 ESR1 (0.40) MAPTNPC1CYP11B1CYP11B2GRM4
SCHEMBL20176808 0.89 MAPT (0.39) MAPTNPC1GRM4CYP1A2CCNT1
SCHEMBL26161267 0.88 CYP11B1 (0.36) NPC1CYP11B1CYP11B2GRM4ESR1
SCHEMBL26161286 0.88 GRM4 (0.34) MAPTNPC1CYP11B1CYP11B2GRM4
SCHEMBL20176832 0.87 ESR1 (0.37) GRM4ESR1ESR2CDK2HDAC6
SCHEMBL20176602 0.87 ESR1 (0.37) GRM4ESR1ESR2CDK2HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2023-06-06 US disclosed
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2023-06-06 US disclosed
WO-2018093231-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME 주식회사 두산 2018-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same OR10J3, ICMT, SLCO4C1 MAPK14 3988/4885PDGFRB 4626/4885PDGFRA 4331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.