SCHEMBL20176668

SCHEMBL20176668

CC(F)(c1cc(Br)c(NC(=O)c2cccc(NC(=O)c3ccccc3)c2F)c(C(F)(F)F)c1)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 10/20 0.46
KCNK3 O14649 1/20 0.44
KCNK9 Q9NPC2 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.43
NR1H4 Q96RI1 3/20 0.42
PPARG P37231 2/20 0.42
PPARA Q07869 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31175827 0.90 RXFP1 (0.47) RXFP1KCNK3KCNK9SMN1; SMN2MEN1
SCHEMBL1766269 0.90 RXFP1 (0.47) RXFP1KCNK3KCNK9SMN1; SMN2MEN1
SCHEMBL18156542 0.88 SMN1; SMN2 (0.42) RXFP1SMN1; SMN2
SCHEMBL1767394 0.88 RXFP1 (0.45) RXFP1KCNK3KCNK9SMN1; SMN2MEN1
SCHEMBL18156541 0.84 RXFP1 (0.48) RXFP1KCNK3KCNK9SMN1; SMN2MEN1
SCHEMBL29422290 0.84 RXFP1 (0.44) RXFP1KCNK3KCNK9SMN1; SMN2MEN1
SCHEMBL1766339 0.84 RXFP1 (0.44) RXFP1KCNK3KCNK9SMN1; SMN2MEN1
SCHEMBL1766943 0.84 RXFP1 (0.44) RXFP1KCNK3KCNK9SMN1; SMN2MEN1
SCHEMBL18069663 0.84 MEN1 (0.38) RXFP1KCNK3KCNK9SMN1; SMN2MEN1
SCHEMBL18156558 0.83 PTGS1 (0.41) RXFP1KCNK3KCNK9SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180199570-A1 USE OF AN INSECTICIDAL CARBOXAMIDE COMPOUND AGAINST PESTS ON CULTIVATED PLANTS BASF AGROCHEMICAL PRODUCTS BV (NL) 2018-07-19 US disclosed
US-20180139960-A1 METHOD FOR CONTROLLING NON-CROP PESTS BASF AGROCHEMICAL PRODUCTS B.V. (NL) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180139960-A1 METHOD FOR CONTROLLING NON-CROP PESTS BCHE, VDAC1, CNDP2 RXFP1 4141/4885KCNK3 3328/4885KCNK9 3556/4885
US-20180199570-A1 USE OF AN INSECTICIDAL CARBOXAMIDE COMPOUND AGAINST PESTS ON CULTIVATED PLANTS AADAC, NAAA, DDT RXFP1 3246/4885KCNK3 2320/4885KCNK9 2348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.