Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20176733 | 0.89 | KDM4E (0.39) | RARBRARAKDM4ERAB9AEIF4A1 | |
| SCHEMBL20176718 | 0.85 | GCGR (0.36) | RARBGCGR | |
| SCHEMBL18217302 | 0.84 | KDM4E (0.30) | KDM4E | |
| SCHEMBL20176722 | 0.84 | RARB (0.34) | RARBGCGR | |
| SCHEMBL20176732 | 0.82 | — | — | |
| SCHEMBL20176729 | 0.81 | RARB (0.35) | RARBRARARARGKDM4ERAB9A | |
| SCHEMBL17694344 | 0.80 | RARB (0.38) | RARBRARARARGKDM4ERAB9A | |
| SCHEMBL17694364 | 0.80 | RARB (0.36) | RARBRARARARGKDM4ERAB9A | |
| SCHEMBL17694315 | 0.80 | RARB (0.40) | RARBRARARARGKDM4ERAB9A | |
| SCHEMBL17694323 | 0.80 | RARB (0.40) | RARBRARARARGKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180142153-A1 | THIADIAZOLOQUINOXALINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-05-24 | — | — | US | disclosed |