Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20176734 | 0.89 | RARB (0.37) | KDM4ERAB9AMEN1KMT2AMAPT | |
| SCHEMBL20176717 | 0.87 | KDM4E (0.41) | KDM4ERAB9AMEN1KMT2AMAPT | |
| SCHEMBL18217174 | 0.87 | KDM4E (0.32) | KDM4ESMN1; SMN2PTPN1EIF4A1 | |
| SCHEMBL20176724 | 0.86 | KDM4E (0.40) | KDM4ERAB9AMEN1KMT2AMAPT | |
| SCHEMBL20176727 | 0.83 | RAB9A (0.42) | KDM4ERAB9AMEN1KMT2AMAPT | |
| SCHEMBL17694341 | 0.82 | KDM4E (0.43) | KDM4ERAB9AMEN1KMT2AMAPT | |
| SCHEMBL20176736 | 0.81 | ALOX15B (0.38) | KDM4ERAB9APTPN1EIF4A1HSD11B1 | |
| SCHEMBL25451093 | 0.79 | KDM4E (0.40) | KDM4ERAB9AMEN1KMT2AMAPT | |
| SCHEMBL16546613 | 0.79 | KDM4E (0.40) | KDM4ERAB9AMEN1KMT2AMAPT | |
| SCHEMBL17694344 | 0.76 | RARB (0.38) | KDM4ERAB9AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180142153-A1 | THIADIAZOLOQUINOXALINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-05-24 | — | — | US | disclosed |