SCHEMBL20176803

SCHEMBL20176803

c1ccc2cc(-c3ccc(-c4c5ccccc5c(-c5ccc(-c6ccc7oc8cc9ccccc9cc8c7c6)cn5)c5ccccc45)cc3)ccc2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 3/20 0.37
CYP11B2 P19099 3/20 0.37
CYP17A1 P05093 1/20 0.37
CYP19A1 P11511 1/20 0.37
ESR1 P03372 3/20 0.34
ESR2 Q92731 3/20 0.34
CYP1A2 P05177 2/20 0.34
GRM4 Q14833 2/20 0.34
NPC1 O15118 2/20 0.34
CASP3 P42574 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
RAB9A P51151 1/20 0.34
SGK1 O00141 3/20 0.33
CLK2 P49760 1/20 0.33
HIPK1 Q86Z02 1/20 0.33
DYRK2 Q92630 1/20 0.33
HIPK2 Q9H2X6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21453211 0.96 CYP11B1 (0.38) CYP11B1CYP11B2CYP17A1CYP19A1ESR1
SCHEMBL26161267 0.94 CYP11B1 (0.36) CYP11B1CYP11B2CYP17A1CYP19A1ESR1
SCHEMBL20176705 0.94 ESR1 (0.40) ESR1ESR2GRM4NPC1MAPT
SCHEMBL26161172 0.94 ESR1 (0.40) ESR1ESR2GRM4NPC1MAPT
SCHEMBL26160909 0.94 ESR1 (0.40) ESR1ESR2GRM4NPC1MAPT
SCHEMBL20176636 0.93 ESR1 (0.40) ESR1ESR2GRM4NPC1MAPT
SCHEMBL26161377 0.92 ESR1 (0.38) ESR1ESR2GRM4MAPT
SCHEMBL26160910 0.89 ESR1 (0.40) CYP11B1CYP11B2ESR1ESR2GRM4
SCHEMBL16067688 0.89 ESR1 (0.42) ESR1ESR2NPC1CASP3SENP7
SCHEMBL26161379 0.88 ESR1 (0.37) ESR1ESR2GRM4NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2023-06-06 US disclosed
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2023-06-06 US disclosed
WO-2018093231-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME 주식회사 두산 2018-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667622-B2 Organic light emitting compound and organic electroluminescence device using same OR10J3, ICMT, SLCO4C1 CYP11B1 836/4885CYP11B2 747/4885CYP17A1 1212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.