Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1579883 | 0.76 | CYP2C9 (0.55) | RAB9AKMT2ASMN1; SMN2CYP2C9L3MBTL1 | |
| SCHEMBL1579880 | 0.76 | CYP2C9 (0.55) | RAB9AKMT2ASMN1; SMN2CYP2C9L3MBTL1 | |
| SCHEMBL1579884 | 0.76 | CYP2C9 (0.55) | RAB9AKMT2ASMN1; SMN2CYP2C9L3MBTL1 | |
| SCHEMBL13826561 | 0.76 | RAB9A (0.43) | RAB9AKMT2ASMN1; SMN2CYP2C9L3MBTL1 | |
| SCHEMBL24135270 | 0.74 | RAB9A (0.46) | RAB9AKMT2ASMN1; SMN2CYP2C9L3MBTL1 | |
| SCHEMBL22311522 | 0.74 | — | — | |
| SCHEMBL25454067 | 0.74 | — | — | |
| SCHEMBL20551511 | 0.71 | CYP2C9 (0.55) | RAB9AKMT2ASMN1; SMN2CYP2C9L3MBTL1 | |
| SCHEMBL8412940 | 0.71 | CYP2C9 (0.55) | RAB9AKMT2ASMN1; SMN2CYP2C9L3MBTL1 | |
| SCHEMBL9449589 | 0.71 | CYP2C9 (0.55) | RAB9AKMT2ASMN1; SMN2CYP2C9L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093569-A1 | SUBSTITUTED BICYCLE HETEROCYCLIC DERIVATIVES USEFUL AS ROMK CHANNEL INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-24 | — | — | WO | disclosed |