Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 19/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24135385 | 0.89 | FGFR4 (0.45) | FGFR4XDH | |
| SCHEMBL21850788 | 0.85 | FGFR4 (0.45) | FGFR4 | |
| SCHEMBL20925345 | 0.75 | FGFR4 (0.47) | FGFR4XDH | |
| SCHEMBL16671048 | 0.74 | FGFR4 (0.55) | FGFR4XDH | |
| SCHEMBL24135186 | 0.72 | FGFR4 (0.41) | FGFR4 | |
| SCHEMBL19930118 | 0.70 | FGFR4 (0.65) | FGFR4 | |
| SCHEMBL28580700 | 0.70 | FGFR4 (0.55) | FGFR4 | |
| SCHEMBL20971487 | 0.69 | FGFR4 (0.65) | FGFR4 | |
| SCHEMBL18095771 | 0.69 | FGFR4 (0.61) | FGFR4 | |
| SCHEMBL23586714 | 0.68 | CNR2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093569-A1 | SUBSTITUTED BICYCLE HETEROCYCLIC DERIVATIVES USEFUL AS ROMK CHANNEL INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-24 | — | — | WO | disclosed |