Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 19/20 | 0.55 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18095771 | 0.84 | FGFR4 (0.61) | FGFR4 | |
| SCHEMBL16671048 | 0.78 | FGFR4 (0.55) | FGFR4 | |
| SCHEMBL18095683 | 0.78 | FGFR4 (0.48) | FGFR4 | |
| SCHEMBL19930118 | 0.77 | FGFR4 (0.65) | FGFR4 | |
| SCHEMBL20971487 | 0.72 | FGFR4 (0.65) | FGFR4 | |
| SCHEMBL20925345 | 0.71 | FGFR4 (0.47) | FGFR4 | |
| SCHEMBL25193614 | 0.70 | FGFR4 (1.00) | FGFR4 | |
| SCHEMBL30437118 | 0.70 | FGFR4 (1.00) | FGFR4 | |
| SCHEMBL18095761 | 0.70 | FGFR4 (0.63) | FGFR4 | |
| SCHEMBL20176927 | 0.70 | FGFR4 (0.49) | FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107667092-B | Formylated N-heterocyclic derivatives as FGFR4 inhibitors | 诺华股份有限公司 | 2021-05-28 | — | — | CN | claimed |
| CN-107667092-B | Formylated N-heterocyclic derivatives as FGFR4 inhibitors | 诺华股份有限公司 | 2021-05-28 | — | — | CN | disclosed |