Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13588632 | 1.00 | TSHR (0.37) | TSHR | |
| SCHEMBL13588635 | 1.00 | TSHR (0.37) | TSHR | |
| SCHEMBL22328994 | 0.86 | TSHR (0.32) | TSHR | |
| SCHEMBL8818203 | 0.85 | TSHR (0.35) | TSHR | |
| SCHEMBL22184096 | 0.84 | ACE2 (0.39) | TSHR | |
| SCHEMBL20663197 | 0.83 | TSHR (0.34) | TSHR | |
| SCHEMBL21507715 | 0.79 | — | — | |
| SCHEMBL13588648 | 0.78 | TSHR (0.31) | TSHR | |
| SCHEMBL13588645 | 0.78 | TSHR (0.31) | TSHR | |
| SCHEMBL573231 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093696-A1 | INDAZOLE DERIVATIVES USEFUL AS INHIBITORS OF DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 | MERCK SHARP & DOHME CORP. (US) | 2018-05-24 | — | — | WO | disclosed |