⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL464424 | 1.00 | — | — | |
| Water SCHEMBL573386 | 1.00 | — | — | |
| Water SCHEMBL573385 | 1.00 | TSHR (0.37) | — | |
| Hydrochloric Acid SCHEMBL16974730 | 0.97 | — | — | |
| SCHEMBL7157362 | 0.90 | TSHR (0.35) | — | |
| SCHEMBL532758 | 0.88 | — | — | |
| SCHEMBL15309950 | 0.88 | TSHR (0.41) | — | |
| Phosphoric Acid SCHEMBL574558 | 0.86 | FDPS (0.43) | — | |
| Phosphoric Acid SCHEMBL574780 | 0.86 | FDPS (0.43) | — | |
| SCHEMBL3671291 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805177-B | Preparation method of saxagliptin intermediate | 河北富格药业有限公司 | 2024-03-01 | — | — | CN | claimed |
| US-20230357269-A1 | NEW MACROCYCLIC LRRK2 KINASE INHIBITORS | ONCODESIGN PRECISION MEDICINE (FR) | 2023-11-09 | — | — | US | claimed |
| CN-114805177-A | Preparation method of saxagliptin intermediate | 河北富格药业有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-112567468-A | Method for lowering blood glucose using dipeptidyl peptidase-4 inhibitor pharmaceutical composition | 阿斯利康(英国)有限公司 | 2021-03-26 | — | — | CN | claimed |
| CN-111138341-A | Preparation method of saxagliptin | 天津民祥生物医药股份有限公司 | 2020-05-12 | — | — | CN | claimed |
| WO-2010146597-A1 | 2-AMINO-2- [8-(DIMETHYL CARBAMOYL)- 8-AZA- BICYCLO [3.2.1] OCT-3-YL]-EXO- ETHANOYL DERIVATIVES AS POTENT DPP-IV INHIBITORS | LUPIN LIMITED (IN) | 2010-12-23 | — | — | WO | claimed |
| CN-118265542-A | Treatment with Ileal Bile Acid Transporter (IBAT) inhibitors to increase Event Free Survival (EFS) | 米鲁姆制药公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| CN-118139623-A | Methods of administering apical sodium-dependent cholic acid transporter inhibitors (ASBTIs) | 米鲁姆制药公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-117836294-A | Biological antagonist containing aromatic ring, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117715642-A | Heterocyclic compounds and methods of use | 薛定谔公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117677664-A | Thermoplastic polyurethane-containing composition | 布拉斯科有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-115417794-B | Preparation method of saxagliptin intermediate | 扬州市三药制药有限公司 | 2024-03-01 | — | — | CN | disclosed |
| EP-0421561-B1 | 24-D-homo-vitamin D-derivatives, a process for their production, pharmaceutical compositions containing them and their use as medicines | SCHERING AG (DE) | 1994-04-06 | — | — | EP | disclosed |
| EP-0454726-A4 | HINDERED LINKING AGENTS AND METHODS | — | 1991-11-27 | — | — | EP | disclosed |
| EP-0454726-A1 | HINDERED LINKING AGENTS AND METHODS | Xoma Corporation (US) | 1991-11-06 | — | — | EP | disclosed |
| EP-0421561-A2 | 24-D-homo-vitamin D-derivatives, a process for their production, pharmaceutical compositions containing them and their use as medicines | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-04-10 | — | — | EP | disclosed |
| WO-1990006774-A1 | HINDERED LINKING AGENTS AND METHODS | XOMA CORPORATION (US) | 1990-06-28 | — | — | WO | disclosed |
| US-4377533-A | PROPYLATION OF NITRILES | SANOFI (FR) | 1983-03-22 | — | — | US | disclosed |
| US-4127607-A | DIPROPYLACETAMIDE BY ACID HYDROLYSIS OF DIPROPYLACETONITRILE WITH SULFURIC ACID | LABAZ (FR) | 1978-11-28 | — | — | US | disclosed |