Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20076534 | 0.79 | — | — | |
| SCHEMBL19019638 | 0.77 | TSHR (0.43) | TSHR | |
| SCHEMBL19336379 | 0.77 | TSHR (0.32) | TSHR | |
| SCHEMBL19504505 | 0.73 | — | — | |
| SCHEMBL1235923 | 0.73 | — | — | |
| SCHEMBL30697044 | 0.73 | — | — | |
| SCHEMBL20177193 | 0.73 | — | — | |
| SCHEMBL14293887 | 0.72 | — | — | |
| SCHEMBL19288183 | 0.71 | TSHR (0.33) | TSHR | |
| SCHEMBL23600870 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093696-A1 | INDAZOLE DERIVATIVES USEFUL AS INHIBITORS OF DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 | MERCK SHARP & DOHME CORP. (US) | 2018-05-24 | — | — | WO | disclosed |