Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.66 |
| ▸ | FPR1 | P21462 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177483 | 0.91 | FPR2 (0.79) | FPR2FPR1SMN1; SMN2MAPT | |
| SCHEMBL20177830 | 0.90 | FPR2 (0.71) | FPR2FPR1SMN1; SMN2MAPTEPHX2 | |
| SCHEMBL20177843 | 0.83 | FPR2 (0.67) | FPR2FPR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL20177479 | 0.81 | FPR2 (0.79) | FPR2FPR1GAAEPHX2 | |
| SCHEMBL18264322 | 0.79 | FPR2 (1.00) | FPR2FPR1 | |
| SCHEMBL18264324 | 0.79 | FPR2 (1.00) | FPR2FPR1 | |
| SCHEMBL20177545 | 0.79 | FPR2 (0.66) | FPR2FPR1SMN1; SMN2GAAMAPT | |
| SCHEMBL20177550 | 0.78 | FPR2 (0.67) | FPR2FPR1KMT2ARAB9AMEN1 | |
| SCHEMBL20177796 | 0.77 | FPR2 (0.82) | FPR2FPR1ALDH1A1MAPT | |
| SCHEMBL20177523 | 0.76 | FPR2 (0.67) | FPR2FPR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |