Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 6/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | FPR1 | P21462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177924 | 0.86 | SLC6A3 (0.55) | PDE4APDE4BPDE4CPDE4DSLC6A4 | |
| SCHEMBL18117707 | 0.86 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DSLC6A4 | |
| SCHEMBL29434235 | 0.86 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DSLC6A4 | |
| SCHEMBL16785350 | 0.86 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DSLC6A4 | |
| SCHEMBL19559436 | 0.86 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DSLC6A4 | |
| SCHEMBL16785489 | 0.86 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DSLC6A4 | |
| SCHEMBL18106605 | 0.86 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DSLC6A4 | |
| SCHEMBL19857212 | 0.85 | KDM4E (0.53) | F2RL1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29434375 | 0.85 | KDM4E (0.53) | F2RL1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16785349 | 0.85 | KDM4E (0.53) | F2RL1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |