Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 8/20 | 0.53 |
| ▸ | VCP | P55072 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29149940 | 1.00 | FBP1 (0.53) | FBP1VCPHSP90AA1ALDH1A1MAPT | |
| SCHEMBL30259520 | 1.00 | FBP1 (0.53) | FBP1VCPHSP90AA1ALDH1A1MAPT | |
| SCHEMBL147060 | 0.82 | FBP1 (0.56) | FBP1VCPHSP90AA1ALDH1A1MAPT | |
| SCHEMBL2077055 | 0.82 | FBP1 (0.56) | FBP1HSP90AA1ALDH1A1MAPTHTT | |
| SCHEMBL2077056 | 0.82 | FBP1 (0.56) | FBP1HSP90AA1ALDH1A1MAPTHTT | |
| SCHEMBL121050 | 0.82 | FBP1 (0.56) | FBP1VCPHSP90AA1ALDH1A1MAPT | |
| SCHEMBL12860019 | 0.79 | VCP (0.53) | FBP1VCPHSP90AA1ALDH1A1MAPT | |
| SCHEMBL1422411 | 0.79 | FBP1 (0.53) | FBP1HSP90AA1ALDH1A1MAPTHTT | |
| SCHEMBL18590413 | 0.79 | FBP1 (0.58) | FBP1VCPALDH1A1MAPTNPSR1 | |
| SCHEMBL17533455 | 0.79 | FBP1 (0.53) | FBP1VCPHSP90AA1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117751110-A | Cycloolefin derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |