Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | FASN | P49327 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28313549 | 1.00 | RECQL (0.57) | RECQLPOLBALDH1A1KDM4ETSHR | |
| SCHEMBL28312550 | 0.94 | RECQL (0.63) | RECQLPOLBALDH1A1KDM4ETSHR | |
| SCHEMBL12489672 | 0.94 | RECQL (0.63) | RECQLPOLBALDH1A1KDM4ETSHR | |
| SCHEMBL11969437 | 0.92 | RECQL (0.61) | RECQLPOLBALDH1A1KDM4ETSHR | |
| SCHEMBL2676212 | 0.88 | RECQL (0.54) | RECQLPOLBALDH1A1KDM4ETSHR | |
| SCHEMBL30072373 | 0.88 | HPGD (0.56) | RECQLPOLBALDH1A1KDM4ETSHR | |
| SCHEMBL15431609 | 0.85 | RECQL (0.55) | RECQLPOLBALDH1A1KDM4ETSHR | |
| SCHEMBL11508133 | 0.85 | CHRNB2 (0.52) | RECQLPOLBALDH1A1KDM4ETSHR | |
| SCHEMBL2677323 | 0.82 | RECQL (0.59) | RECQLPOLBALDH1A1KDM4ETSHR | |
| SCHEMBL22874739 | 0.81 | RECQL (0.51) | RECQLPOLBALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981910-B2 | Substituted pyrrolidines and methods of use | ABBVIE S.Á.R.L. (LU) | 2018-05-29 | — | — | US | disclosed |