Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.49 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | OTC | P00480 | 1/20 | 0.44 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.42 |
| ▸ | RRM1 | P23921 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 5/20 | 0.41 |
| ▸ | NOS1 | P29475 | 4/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16447289 | 1.00 | DPP7 (0.49) | DPP7GNAI3GNAO1GNAI1NOD1 | |
| SCHEMBL22508731 | 0.87 | OTC (0.44) | DPP7GNAI3GNAO1GNAI1NOD1 | |
| SCHEMBL25212167 | 0.86 | DPP7 (0.49) | DPP7GNAI3GNAO1GNAI1NOD1 | |
| SCHEMBL25267071 | 0.86 | DPP7 (0.49) | DPP7GNAI3GNAO1GNAI1NOD1 | |
| SCHEMBL20178595 | 0.84 | OTC (0.46) | OTCDDAH1GSRNOS2NOS1 | |
| SCHEMBL16446596 | 0.84 | OTC (0.46) | OTCDDAH1GSRNOS2NOS1 | |
| SCHEMBL15618245 | 0.83 | OTC (0.51) | NOD1OTCDDAH1GSRNOS2 | |
| SCHEMBL15483719 | 0.82 | OTC (0.50) | NOD1OTCDDAH1GSRNOS2 | |
| SCHEMBL13464207 | 0.81 | OTC (0.52) | NOD1OTCDDAH1GSRNOS2 | |
| SCHEMBL22691090 | 0.81 | OTC (0.52) | NOD1OTCDDAH1GSRNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981908-B2 | Amino acid derivatives | MEDIMMUNE LIMITED (GB) | 2018-05-29 | — | — | US | disclosed |