Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 6/20 | 0.38 |
| ▸ | NOS1 | P29475 | 4/20 | 0.38 |
| ▸ | NOS3 | P29474 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16447289 | 0.87 | DPP7 (0.49) | OTCGSRGNAI3GNAO1GNAI1 | |
| SCHEMBL20178598 | 0.87 | DPP7 (0.49) | OTCGSRGNAI3GNAO1GNAI1 | |
| SCHEMBL20178595 | 0.80 | OTC (0.46) | OTCGSRDDAH1NOS2NOS1 | |
| SCHEMBL16446596 | 0.80 | OTC (0.46) | OTCGSRDDAH1NOS2NOS1 | |
| SCHEMBL15618245 | 0.79 | OTC (0.51) | OTCGSRDDAH1NOS2NOS1 | |
| SCHEMBL15483719 | 0.77 | OTC (0.50) | OTCGSRDDAH1NOS2NOS1 | |
| SCHEMBL13464207 | 0.77 | OTC (0.52) | OTCGSRDDAH1NOS2NOS1 | |
| SCHEMBL22691090 | 0.77 | OTC (0.52) | OTCGSRDDAH1NOS2NOS1 | |
| SCHEMBL13445977 | 0.77 | OTC (0.52) | OTCGSRDDAH1NOS2NOS1 | |
| SCHEMBL15618211 | 0.76 | OTC (0.49) | OTCGSRDDAH1NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030545-B1 | AMINO ACID DERIVATIVES | MEDIMMUNE LTD (GB) | 2020-10-07 | — | — | EP | disclosed |