Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20178961 | 0.92 | TGFBR1 (0.77) | TGFBR1 | |
| SCHEMBL18005166 | 0.90 | TGFBR1 (1.00) | TGFBR1 | |
| SCHEMBL18005146 | 0.88 | TGFBR1 (1.00) | TGFBR1 | |
| SCHEMBL18005228 | 0.85 | TGFBR1 (1.00) | TGFBR1 | |
| SCHEMBL18005153 | 0.83 | TGFBR1 (1.00) | TGFBR1 | |
| SCHEMBL18005211 | 0.83 | TGFBR1 (0.79) | TGFBR1 | |
| SCHEMBL18005411 | 0.81 | TGFBR1 (1.00) | TGFBR1 | |
| SCHEMBL18005322 | 0.77 | TGFBR1 (0.69) | TGFBR1 | |
| SCHEMBL20178958 | 0.76 | TGFBR1 (0.77) | TGFBR1 | |
| SCHEMBL18005286 | 0.76 | TGFBR1 (1.00) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981944-B2 | GDF-8 inhibitors | RIGEL PHARMACEUTICALS, INC (US) | 2018-05-29 | — | — | US | claimed |