SCHEMBL20178973

SCHEMBL20178973

Cc1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2CCCO)cc1C(C)(C)C

nearest known ligand 0.72

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RARG P13631 19/20 0.72
RARA P10276 19/20 0.72
RARB P10826 18/20 0.72
RXRA P19793 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL381582 0.84 RARG (1.00) RARGRARARARB
Hydrochloric Acid SCHEMBL382480 0.83 RARG (1.00) RARGRARARARB
SCHEMBL382731 0.82 RARG (0.73) RARGRARARARB
SCHEMBL382095 0.81 RARG (1.00) RARGRARARARB
SCHEMBL382047 0.75 RARG (0.83) RARGRARARARB
SCHEMBL382630 0.74 RARG (0.79) RARGRARARARB
SCHEMBL497953 0.74 RARB (0.87) RARGRARARARBRXRA
SCHEMBL382137 0.73 RARG (0.79) RARGRARARARB
SCHEMBL382177 0.72 RARG (0.79) RARGRARARARB
SCHEMBL28961526 0.71 RARG (0.48) RARGRARARARBRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018090137-A1 METHODS FOR TREATING MULTIPLE OSTEOCHONDROMA (MO) Clementia Pharmaceuticals Inc. (CA) 2018-05-24 WO disclosed