Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20174500 | 0.95 | CYP1A1 (0.37) | CYP1A1CYP1B1S1PR5S1PR4KDM4E | |
| SCHEMBL20174496 | 0.94 | CYP1A1 (0.38) | CYP1A1CYP1B1S1PR5S1PR4KDM4E | |
| SCHEMBL20174503 | 0.89 | CYP1A1 (0.40) | CYP1A1CYP1B1S1PR5S1PR4KDM4E | |
| SCHEMBL20174538 | 0.88 | MEN1 (0.37) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL20174502 | 0.87 | CYP1A1 (0.39) | CYP1A1CYP1B1S1PR5S1PR4KDM4E | |
| SCHEMBL20174461 | 0.87 | MAPT (0.34) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL20174442 | 0.87 | MEN1 (0.36) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL20174507 | 0.86 | CYP1A1 (0.39) | CYP1A1CYP1B1S1PR5S1PR4KDM4E | |
| SCHEMBL20174501 | 0.86 | MEN1 (0.37) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL20174495 | 0.84 | CYP1A1 (0.38) | CYP1A1CYP1B1S1PR5S1PR4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | CRY1, NR2E3, ERG | CYP1A1 726/4885CYP1B1 725/4885S1PR5 3034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.