Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21581862 | 1.00 | GAA (0.47) | GAALMNAHTTHPGDALDH1A1 | |
| SCHEMBL18628006 | 0.89 | GAA (0.48) | GAALMNAHTTHPGDALDH1A1 | |
| SCHEMBL18628005 | 0.89 | GAA (0.48) | GAALMNAHTTHPGDALDH1A1 | |
| SCHEMBL20386965 | 0.89 | GAA (0.48) | GAALMNAHTTHPGDALDH1A1 | |
| SCHEMBL18628012 | 0.87 | GAA (0.49) | GAALMNAHTTHPGDALDH1A1 | |
| SCHEMBL18628011 | 0.87 | GAA (0.49) | GAALMNAHTTHPGDALDH1A1 | |
| SCHEMBL18656994 | 0.87 | GAA (0.49) | GAALMNAHTTHPGDALDH1A1 | |
| SCHEMBL21581856 | 0.86 | GAA (0.48) | GAALMNAHTTHPGDALDH1A1 | |
| SCHEMBL20179294 | 0.86 | GAA (0.48) | GAALMNAHTTHPGDALDH1A1 | |
| SCHEMBL18628000 | 0.85 | GAA (0.54) | GAALMNAHTTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541773-B1 | ASYMMETRICALLY SUBSTITUTED BIS-ALKENYL DIPHENYL ETHERS, THEIR PREPARATION AND USE | EVONIK OPERATIONS GMBH (DE) | 2020-05-13 | — | — | EP | disclosed |
| US-20190367652-A1 | ASYMMETRICALLY SUBSTITUTED BIS-ALKENYL DIPHENYL ETHERS, THEIR PREPARATION AND USE | EVONIK TECHNOCHEMIE GMBH (DE) | 2019-12-05 | — | — | US | disclosed |
| WO-2018091253-A1 | ASYMMETRICALLY SUBSTITUTED BIS-ALKENYL DIPHENYL ETHERS, THEIR PREPARATION AND USE | EVONIK TECHNOCHEMIE GMBH (DE) | 2018-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190367652-A1 | ASYMMETRICALLY SUBSTITUTED BIS-ALKENYL DIPHENYL ETHERS, THEIR PREPARATION AND USE | ITGB3, C9, CBR3 | GAA 4773/4885LMNA 208/4885HTT 3281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.