Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 17/20 | 0.75 |
| ▸ | SLC22A12 | Q96S37 | 11/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | CASP1 | P29466 | 1/20 | 0.65 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | CASP7 | P55210 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17010244 | 0.87 | XDH (0.77) | XDHSLC22A12KDM4EMEN1USP2 | |
| SCHEMBL22364235 | 0.86 | XDH (1.00) | XDHSLC22A12KDM4EMEN1USP2 | |
| SCHEMBL16700088 | 0.85 | XDH (1.00) | XDHSLC22A12KDM4EMEN1USP2 | |
| SCHEMBL22364227 | 0.83 | KDM4E (0.77) | XDHSLC22A12KDM4EMEN1USP2 | |
| SCHEMBL17010240 | 0.82 | XDH (0.78) | XDHSLC22A12KDM4EMEN1USP2 | |
| SCHEMBL16708623 | 0.82 | XDH (0.78) | XDHSLC22A12KDM4EMEN1USP2 | |
| SCHEMBL10926831 | 0.82 | SLC22A12 (1.00) | XDHSLC22A12KDM4EMEN1USP2 | |
| SCHEMBL19760871 | 0.82 | XDH (0.72) | XDHSLC22A12KDM4EMEN1USP2 | |
| SCHEMBL17941574 | 0.81 | XDH (0.70) | XDHSLC22A12KDM4EMEN1USP2 | |
| SCHEMBL19092939 | 0.79 | XDH (1.00) | XDHSLC22A12KDM4EMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018005192-A9 | COMPOUNDS AND THEIR USE FOR REDUCING URIC ACID LEVELS | ACQUIST LLC (US) | 2018-05-24 | — | — | WO | disclosed |