Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | FPR3 | P25089 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15920926 | 1.00 | HRH3 (0.54) | HRH3ALDH1A1MAPTALOX15SMN1; SMN2 | |
| SCHEMBL9856869 | 0.98 | SMN1; SMN2 (0.53) | HRH3ALDH1A1MAPTALOX15SMN1; SMN2 | |
| SCHEMBL28390299 | 0.98 | PAOX (0.53) | HRH3ALDH1A1MAPTALOX15SMN1; SMN2 | |
| SCHEMBL11732584 | 0.93 | SMN1; SMN2 (0.60) | HRH3ALDH1A1MAPTALOX15SMN1; SMN2 | |
| SCHEMBL2127041 | 0.93 | SMN1; SMN2 (0.60) | HRH3ALDH1A1MAPTALOX15SMN1; SMN2 | |
| SCHEMBL25751543 | 0.93 | TSHR (0.52) | HRH3ALDH1A1MAPTALOX15SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4924873 | 0.91 | SMN1; SMN2 (0.58) | HRH3ALDH1A1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL1856574 | 0.91 | SMN1; SMN2 (0.57) | HRH3ALDH1A1MAPTALOX15SMN1; SMN2 | |
| SCHEMBL15150928 | 0.87 | TSHR (0.54) | HRH3ALDH1A1MAPTSMN1; SMN2CYP1A2 | |
| Formic Acid SCHEMBL28117669 | 0.86 | SMN1; SMN2 (0.53) | HRH3ALDH1A1MAPTALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541375-B1 | FACTOR XIIA INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2021225968-A1 | LUMINALLY-ACTING N-(PIPERIDIN-4-YL)BENZAMIDE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-11-11 | — | — | WO | disclosed |
| WO-2021032933-A1 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-02-25 | — | — | WO | disclosed |
| WO-2018093695-A1 | FACTOR XIIa INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2018-05-24 | — | — | WO | disclosed |