Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | CA3 | P07451 | 2/20 | 0.59 |
| ▸ | CA5A | P35218 | 2/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27056159 | 0.87 | MEN1 (0.66) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL19787026 | 0.87 | MEN1 (0.59) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL2000676 | 0.86 | EPHX1 (0.69) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL16489188 | 0.83 | TSHR (0.67) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL13861685 | 0.82 | ALDH1A1 (0.79) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL23568850 | 0.82 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL7701423 | 0.81 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL20684934 | 0.81 | MEN1 (0.68) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27202275 | 0.80 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL29982917 | 0.80 | MEN1 (1.00) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10442890-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | VANDERBILT UNIVERSITY (US) | 2019-10-15 | — | — | US | disclosed |
| US-20180142061-A1 | Multifunctional Degradable Nanoparticles with Control over Size and Functionalities | UNIV VANDERBILT (US) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10442890-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | DSTN, PARN, CTSA | MEN1 1242/4885KMT2A 3937/4885ALDH1A1 1776/4885 |
| US-20180142061-A1 | Multifunctional Degradable Nanoparticles with Control over Size and Functionalities | DSTN, PARN, CTSA | MEN1 1242/4885KMT2A 3937/4885ALDH1A1 1776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.