Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23561784 | 1.00 | ESR1 (0.53) | ESR1 | |
| SCHEMBL26267987 | 0.88 | ESR1 (0.45) | ESR1 | |
| SCHEMBL24022096 | 0.87 | MAOA (0.50) | ESR1 | |
| SCHEMBL21729988 | 0.86 | ESR1 (0.50) | ESR1 | |
| SCHEMBL20165305 | 0.86 | ESR1 (0.54) | ESR1 | |
| SCHEMBL20165147 | 0.86 | ESR1 (0.54) | ESR1 | |
| SCHEMBL21724882 | 0.86 | ESR1 (0.66) | ESR1 | |
| SCHEMBL21724881 | 0.86 | ESR1 (0.66) | ESR1 | |
| SCHEMBL23529265 | 0.86 | CHRM2 (0.58) | ESR1 | |
| SCHEMBL23474850 | 0.85 | ESR1 (0.50) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3847157-B1 | PROCESS FOR THE PREPARATION OF METHYL 6-(2,4-DICHLOROPHENYL)-5-[4-[(3S)-1-(3-FLUOROPROPYL)PYRROLIDIN-3-YL]OXYPHENYL]-8,9-DIHYDRO-7H-BENZO[7]ANNULENE-2-CARBOXYLATE AND A SALT THEREOF | SANOFI SA (FR) | 2022-05-18 | — | — | EP | disclosed |
| WO-2018091153-A1 | NOVEL SUBSTITUTED N-(3-FLUOROPROPYL)-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2018-05-24 | — | — | WO | disclosed |