Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 2/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.51 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.50 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22664150 | 1.00 | SCN1A (0.51) | SCN1ASCN2ASCN3ACHEK2UTS2R | |
| SCHEMBL3458256 | 0.93 | SCN1A (0.56) | SCN1ASCN2ASCN3ACHEK2CA1 | |
| Hydrochloric Acid SCHEMBL6444714 | 0.91 | SCN1A (0.55) | SCN1ASCN2ASCN3ACHEK2CA1 | |
| SCHEMBL22664149 | 0.85 | ALDH1A1 (0.55) | CHEK2UTS2RACACBEPHX2HRH3 | |
| SCHEMBL17869370 | 0.85 | ALDH1A1 (0.55) | CHEK2UTS2RACACBEPHX2HRH3 | |
| SCHEMBL17869387 | 0.85 | SCN1A (0.51) | SCN1ASCN2ASCN3ACHEK2UTS2R | |
| SCHEMBL20165095 | 0.85 | KMT2A (0.46) | CA1CA2MEN1KMT2AEPHX2 | |
| SCHEMBL20165094 | 0.85 | KMT2A (0.46) | CA1CA2MEN1KMT2AEPHX2 | |
| SCHEMBL16147114 | 0.82 | EPHX2 (0.61) | CA1CA2MEN1KMT2AEPHX2 | |
| SCHEMBL21842091 | 0.82 | SCN1A (0.52) | SCN1ASCN2ASCN3ACHEK2UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091153-A1 | NOVEL SUBSTITUTED N-(3-FLUOROPROPYL)-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2018-05-24 | — | — | WO | disclosed |