Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.39 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20179672 | 1.00 | HTR2C (0.40) | HTR2CHTR2BHTR2APRKCZACVR1B | |
| Hydrochloric Acid SCHEMBL29756772 | 0.99 | HTR2C (0.39) | HTR2CHTR2BHTR2APRKCZACVR1B | |
| Hydrochloric Acid SCHEMBL20165096 | 0.99 | HTR2C (0.39) | HTR2CHTR2BHTR2APRKCZACVR1B | |
| Hydrochloric Acid SCHEMBL20165098 | 0.99 | HTR2C (0.39) | HTR2CHTR2BHTR2APRKCZACVR1B | |
| SCHEMBL20165126 | 0.87 | ESR1 (0.47) | HTR2CHTR2BPRKCZESR1 | |
| SCHEMBL20165130 | 0.87 | ESR1 (0.47) | HTR2CHTR2BPRKCZESR1 | |
| SCHEMBL29756847 | 0.87 | ESR1 (0.47) | HTR2CHTR2BPRKCZESR1 | |
| SCHEMBL30624598 | 0.78 | PRKCZ (0.41) | HTR2CHTR2BPRKCZ | |
| SCHEMBL26187437 | 0.78 | PRKCZ (0.41) | HTR2CHTR2BPRKCZ | |
| SCHEMBL26187427 | 0.78 | PRKCZ (0.41) | HTR2CHTR2BPRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091153-A1 | NOVEL SUBSTITUTED N-(3-FLUOROPROPYL)-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2018-05-24 | — | — | WO | disclosed |