Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 13/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20165337 | 0.80 | ELANE (0.40) | ELANECTSLCA2 | |
| SCHEMBL20165197 | 0.72 | ELANE (0.40) | ELANECA2 | |
| SCHEMBL20179710 | 0.69 | ELANE (0.45) | ELANECA2MEN1KMT2ARYR2 | |
| SCHEMBL20179807 | 0.67 | MAPT (0.38) | ELANECA2MEN1KMT2A | |
| SCHEMBL20179699 | 0.64 | ELANE (0.38) | ELANECA2MEN1KMT2A | |
| SCHEMBL20165128 | 0.63 | KDM4E (0.63) | ELANECA2MEN1KMT2A | |
| SCHEMBL29756838 | 0.63 | KDM4E (0.63) | ELANECA2MEN1KMT2A | |
| SCHEMBL20179709 | 0.63 | ELANE (0.46) | ELANECA2MEN1KMT2A | |
| SCHEMBL20165113 | 0.62 | KDM4E (0.53) | ELANECA2MEN1KMT2A | |
| SCHEMBL22664171 | 0.62 | ELANE (0.42) | ELANECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091153-A1 | NOVEL SUBSTITUTED N-(3-FLUOROPROPYL)-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2018-05-24 | — | — | WO | disclosed |