Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ELANE | P08246 | 7/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20165456 | 0.83 | ELANE (0.38) | MAPTMEN1KMT2AELANEESR1 | |
| SCHEMBL20179806 | 0.83 | ELANE (0.38) | MAPTMEN1KMT2AELANEESR1 | |
| SCHEMBL20179642 | 0.76 | ELANE (0.42) | MAPTMEN1KMT2AELANEESR1 | |
| SCHEMBL20179643 | 0.73 | GRM5 (0.63) | MAPTMEN1KMT2AGRM5HSD17B10 | |
| SCHEMBL20179641 | 0.72 | ELANE (0.39) | MAPTMEN1KMT2AELANEESR1 | |
| SCHEMBL20165031 | 0.72 | ELANE (0.39) | MAPTMEN1KMT2AELANEESR1 | |
| SCHEMBL29756860 | 0.72 | ELANE (0.39) | MAPTMEN1KMT2AELANEESR1 | |
| SCHEMBL20165273 | 0.71 | GRM5 (0.54) | MAPTMEN1KMT2AELANEESR1 | |
| SCHEMBL20179742 | 0.67 | MEN1 (0.35) | MEN1KMT2AELANEESR1ESR2 | |
| SCHEMBL20179690 | 0.67 | ELANE (0.37) | MEN1KMT2AELANECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091153-A1 | NOVEL SUBSTITUTED N-(3-FLUOROPROPYL)-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2018-05-24 | — | — | WO | disclosed |