Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29756929 | 0.92 | ESR1 (0.68) | ESR1 | |
| SCHEMBL20168871 | 0.92 | ESR1 (0.68) | ESR1 | |
| SCHEMBL21253393 | 0.91 | ESR1 (0.81) | ESR1 | |
| SCHEMBL20179708 | 0.84 | ESR1 (0.73) | ESR1 | |
| SCHEMBL24022020 | 0.84 | ESR1 (0.71) | ESR1 | |
| SCHEMBL21253465 | 0.84 | ESR1 (0.81) | ESR1 | |
| SCHEMBL24022088 | 0.84 | ESR1 (0.81) | ESR1 | |
| SCHEMBL23336103 | 0.83 | ESR1 (0.65) | ESR1 | |
| SCHEMBL19132028 | 0.83 | ESR1 (0.82) | ESR1 | |
| SCHEMBL29499999 | 0.83 | ESR1 (0.82) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091153-A1 | NOVEL SUBSTITUTED N-(3-FLUOROPROPYL)-PYRROLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2018-05-24 | — | — | WO | disclosed |