Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21253393 | 0.87 | ESR1 (0.81) | ESR1 | |
| SCHEMBL23335919 | 0.85 | ESR1 (0.62) | ESR1 | |
| SCHEMBL20179754 | 0.83 | ESR1 (0.68) | ESR1 | |
| SCHEMBL23335688 | 0.83 | ESR1 (0.66) | ESR1 | |
| SCHEMBL21253000 | 0.82 | ESR1 (0.48) | ESR1 | |
| SCHEMBL23335797 | 0.82 | ESR1 (0.64) | ESR1 | |
| SCHEMBL23336078 | 0.81 | ESR1 (0.60) | ESR1 | |
| SCHEMBL23335616 | 0.80 | ESR1 (0.65) | ESR1 | |
| SCHEMBL24022020 | 0.80 | ESR1 (0.71) | ESR1 | |
| SCHEMBL24022088 | 0.80 | ESR1 (0.81) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3416962-B1 | 6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES AS ESTROGEN RECEPTOR MODULATORS | SANOFI SA (FR) | 2021-05-05 | — | — | EP | disclosed |