Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26205579 | 0.86 | CYP1A2 (0.31) | — | |
| SCHEMBL26723963 | 0.81 | — | — | |
| SCHEMBL21191222 | 0.77 | PTGIR (0.36) | PTGIRPTGDR | |
| SCHEMBL23996185 | 0.77 | ATM (0.37) | PTGIRPTGDR | |
| SCHEMBL22329082 | 0.77 | — | — | |
| SCHEMBL22329139 | 0.76 | PTGIR (0.33) | PTGIRPTGDR | |
| SCHEMBL20179888 | 0.74 | DPP4 (0.32) | — | |
| SCHEMBL22329076 | 0.73 | DPP4 (0.31) | — | |
| SCHEMBL22329102 | 0.70 | PTGIR (0.30) | PTGIR | |
| SCHEMBL20179869 | 0.70 | FFAR1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200253971-A1 | DIHYDROPYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2020-08-13 | — | — | US | disclosed |
| WO-2018090862-A1 | DIHYDROPYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2018-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200253971-A1 | DIHYDROPYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF | DPYD, DHPS, HPRT1 | PTGIR 3067/4885PTGDR 3247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.