SCHEMBL20179877

SCHEMBL20179877

CN1CC(F)C(COCC(=O)O)C1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 2/20 0.30
PTGDR Q13258 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22329082 0.80
SCHEMBL21191158 0.75 PTGIR (0.31) PTGIRPTGDR
SCHEMBL20179859 0.74
SCHEMBL23996187 0.73 ATM (0.33)
SCHEMBL22329102 0.73 PTGIR (0.30) PTGIR
SCHEMBL22166895 0.72
SCHEMBL20179870 0.70 CYP2D6 (0.35)
SCHEMBL22329115 0.69 SLC6A9 (0.33)
SCHEMBL20179869 0.69 FFAR1 (0.34)
SCHEMBL23996172 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018090862-A1 DIHYDROPYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2018-05-24 WO disclosed