Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 20/20 | 0.82 |
| ▸ | ABHD6 | Q9BV23 | 6/20 | 0.65 |
| ▸ | PLA2G7 | Q13093 | 5/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20158328 | 0.90 | MGLL (0.80) | MGLLABHD6PLA2G7 | |
| SCHEMBL20136984 | 0.90 | MGLL (1.00) | MGLLABHD6PLA2G7 | |
| SCHEMBL20158270 | 0.87 | MGLL (0.79) | MGLLABHD6PLA2G7 | |
| SCHEMBL20137042 | 0.87 | MGLL (1.00) | MGLLABHD6PLA2G7 | |
| SCHEMBL28880215 | 0.83 | MGLL (0.72) | MGLLABHD6PLA2G7 | |
| SCHEMBL21993876 | 0.82 | MGLL (0.71) | MGLLABHD6PLA2G7 | |
| SCHEMBL21571708 | 0.82 | MGLL (0.81) | MGLLABHD6PLA2G7 | |
| SCHEMBL20151757 | 0.81 | MGLL (0.83) | MGLLABHD6PLA2G7 | |
| SCHEMBL20136962 | 0.81 | MGLL (1.00) | MGLLABHD6PLA2G7 | |
| SCHEMBL20151812 | 0.80 | MGLL (0.81) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093947-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |