Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 13/20 | 0.41 |
| ▸ | CA2 | P00918 | 13/20 | 0.41 |
| ▸ | CA4 | P22748 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | EYA2 | O00167 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22147372 | 0.89 | TDP1 (0.47) | CA1CA2CA4ALDH1A1KMT2A | |
| SCHEMBL14341631 | 0.82 | NR1D1 (0.40) | CA1CA2CA4NR1D1 | |
| SCHEMBL12198408 | 0.78 | NPC1 (0.47) | ALDH1A1KMT2ATDP1CA12CA9 | |
| SCHEMBL10958880 | 0.78 | NR1D1 (0.51) | ALDH1A1NR1D1KMT2AKDM4ELMNA | |
| Edetic Acid SCHEMBL3810362 | 0.76 | TDP1 (0.64) | CA1CA2CA4KMT2ATDP1 | |
| SCHEMBL5852235 | 0.76 | TDP1 (0.64) | CA1CA2CA4KMT2ATDP1 | |
| SCHEMBL5852270 | 0.76 | TDP1 (0.64) | CA1CA2CA4KMT2ATDP1 | |
| SCHEMBL13129733 | 0.76 | TDP1 (0.64) | CA1CA2CA4KMT2ATDP1 | |
| SCHEMBL5085940 | 0.76 | TDP1 (0.64) | CA1CA2CA4KMT2ATDP1 | |
| SCHEMBL14355755 | 0.76 | NR1D1 (0.43) | ALDH1A1NR1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541368-B1 | IMAGEABLE PARTICLES, METHODS OF MAKING AND METHODS OF USE THEREOF | US HEALTH (US) | 2023-07-12 | — | — | EP | disclosed |
| WO-2018093566-A1 | IMAGEABLE PARTICLES, METHODS OF MAKING AND METHODS OF USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-05-24 | — | — | WO | disclosed |