Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 7/20 | 0.48 |
| ▸ | NOS1 | P29475 | 7/20 | 0.48 |
| ▸ | NOS2 | P35228 | 7/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19412595 | 0.80 | NOS3 (0.50) | NOS3NOS1NOS2 | |
| SCHEMBL25322486 | 0.80 | NOS3 (0.50) | NOS3NOS1NOS2 | |
| SCHEMBL25322022 | 0.68 | NOS3 (0.42) | NOS3NOS1NOS2 | |
| SCHEMBL25322026 | 0.68 | NOS3 (0.42) | NOS3NOS1NOS2 | |
| SCHEMBL13198582 | 0.67 | — | — | |
| SCHEMBL18309012 | 0.65 | — | — | |
| SCHEMBL16305185 | 0.65 | — | — | |
| SCHEMBL25319339 | 0.64 | NOS3 (0.52) | NOS3NOS1NOS2 | |
| SCHEMBL20860634 | 0.63 | — | — | |
| SCHEMBL25319623 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093920-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | MERIAL, INC. (US) | 2018-05-24 | — | — | WO | disclosed |