Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.86 |
| ▸ | ESR1 | P03372 | 4/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16094788 | 0.96 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL1301471 | 0.96 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL11863762 | 0.93 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL2511593 | 0.93 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL8875 | 0.93 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL11308163 | 0.93 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL11072538 | 0.93 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL8762087 | 0.93 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL4625155 | 0.93 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| Hydrochloric Acid SCHEMBL7006332 | 0.93 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117224675-B | Two-dimensional flower-like water-soluble photo-thermal conversion nano material, synthesis method thereof and near infrared application | 湖北大学 | 2026-05-15 | — | — | CN | claimed |
| CN-120040461-A | Spirobarbitudes compound, preparation method and application | 北京工业大学 | 2025-05-27 | — | — | CN | claimed |
| CN-119954758-A | Synthesis method of natural product Hypermonone G | 贵州大学 | 2025-05-09 | — | — | CN | claimed |
| CN-116174032-B | Anti-loss gold-based catalyst and preparation method and application thereof | 内蒙古鄂尔多斯电力冶金集团股份有限公司 | 2025-01-28 | — | — | CN | claimed |
| CN-119080072-A | Preparation method of gold-doped sulfide material | 中南大学 | 2024-12-06 | — | — | CN | claimed |
| CN-118795000-A | Preparation method and application of electrochemical sensor based on metal cluster composite material | 江苏大学 | 2024-10-18 | — | — | CN | claimed |
| CN-118724716-A | Method for preparing oxalic acid diester compound by using gold-based catalyst | 中国科学院兰州化学物理研究所 | 2024-10-01 | — | — | CN | claimed |
| CN-116283772-B | Compound with cyclobutene structure and preparation method and application thereof | 华南理工大学 | 2024-09-03 | — | — | CN | claimed |
| CN-118527666-A | CsPbBr3Preparation method of-Au heterogeneous superlattice | 吉林大学 | 2024-08-23 | — | — | CN | claimed |
| CN-118359662-A | Monovalent gold complex containing triphenylphosphine group, and preparation method and application thereof | 江西科技师范大学 | 2024-07-19 | — | — | CN | claimed |
| CN-113354676-A | Cysteine fluorescent probe and preparation method and application thereof | 香港理工大学深圳研究院 | 2021-09-07 | — | — | CN | claimed |
| CN-107879967-B | Preparation method of 1-azaspiro [4.4] nonane-6-ketone | 上海交通大学 | 2021-07-27 | — | — | CN | claimed |
| CN-113042067-A | Method for preparing hydrogen transfer catalyst based on waste lithium battery cathode carbon material | 中国矿业大学 | 2021-06-29 | — | — | CN | claimed |
| CN-112547057-A | Gold catalyst for producing vinyl chloride monomer by calcium carbide method and preparation method thereof | 浙江工业大学 | 2021-03-26 | — | — | CN | claimed |
| CN-108671961-B | Ruthenium complex photocatalyst, preparation method and application thereof | 三峡大学 | 2021-01-26 | — | — | CN | claimed |
| CN-112010886-A | Pyrroloxazine ring compound and preparation method thereof | 复旦大学 | 2020-12-01 | — | — | CN | claimed |
| CN-111484462-A | 4-isoxazoline compound and preparation method thereof | 南京工业大学 | 2020-08-04 | — | — | CN | claimed |
| CN-111299816-A | Method for preparing gold nanoparticle microsensor by utilizing laser deposition and application | 吉林大学 | 2020-06-19 | — | — | CN | claimed |
| CN-111175353-A | Method for preparing micro-nano-wire by using laser technology and application thereof | 吉林大学 | 2020-05-19 | — | — | CN | claimed |
| CN-108069961-B | Method for preparing tetrahydrobenzo [ b ] [1,8] naphthyridine compound | 中国科学院大连化学物理研究所 | 2020-04-21 | — | — | CN | claimed |