Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | GAK | O14976 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14137199 | 0.82 | EGFR (0.57) | EGFRRAPGEF4ABCG2EPAS1MEN1 | |
| SCHEMBL14339391 | 0.78 | EGFR (0.54) | EGFRRAPGEF4ABCG2EPAS1MEN1 | |
| SCHEMBL16020286 | 0.77 | EGFR (0.53) | EGFRRAPGEF4ABCG2EPAS1MEN1 | |
| SCHEMBL20609306 | 0.74 | RAPGEF4 (0.59) | EGFRRAPGEF4ABCG2EPAS1MEN1 | |
| SCHEMBL18440260 | 0.74 | EGFR (0.50) | EGFRRAPGEF4ABCG2EPAS1MEN1 | |
| SCHEMBL1519246 | 0.74 | MAPT (0.62) | EGFRRAPGEF4MEN1KMT2AKDM4E | |
| SCHEMBL20180549 | 0.73 | EGFR (0.47) | EGFRRAPGEF4ABCG2EPAS1MEN1 | |
| SCHEMBL29961149 | 0.73 | RAPGEF4 (0.61) | EGFRRAPGEF4ABCG2EPAS1MEN1 | |
| SCHEMBL29961547 | 0.73 | RAPGEF4 (0.61) | EGFRRAPGEF4ABCG2EPAS1MEN1 | |
| SCHEMBL1687027 | 0.73 | RAPGEF4 (0.61) | EGFRRAPGEF4ABCG2EPAS1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093107-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | 주식회사 두산 | 2018-05-24 | — | — | WO | disclosed |