SCHEMBL20180340

SCHEMBL20180340

Brc1cccc(-c2ccc3sccc3c2)c1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.53
CA2 P00918 9/20 0.45
CA12 O43570 9/20 0.45
ALDH1A1 P00352 2/20 0.44
RAB9A P51151 2/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
HK1 P19367 1/20 0.44
HKDC1 Q2TB90 1/20 0.44
BIRC5 O15392 1/20 0.42
CYP2A6 P11509 2/20 0.41
ENPP1 P22413 1/20 0.39
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
CYP1A2 P05177 1/20 0.38
KMT2A Q03164 1/20 0.38
PIK3CD O00329 1/20 0.37
KDM1A O60341 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20984002 0.83 DYRK1A (0.58) DYRK1ACA2CA12ALDH1A1CYP2A6
SCHEMBL25061130 0.83 DYRK1A (0.58) DYRK1ACA2CA12ALDH1A1CYP2A6
SCHEMBL27864617 0.81 CA2 (0.57) DYRK1ACA2CA12CYP2A6ENPP1
SCHEMBL2036162 0.81 CA2 (0.60) DYRK1ACA2CA12CYP2A6ENPP1
SCHEMBL226062 0.78 CYP2A6 (0.50) DYRK1ACA2CA12ALDH1A1MAPT
SCHEMBL30714252 0.78 CYP2A6 (0.50) DYRK1ACA2CA12ALDH1A1MAPT
SCHEMBL28744555 0.76 CA2 (0.60) DYRK1ACA2CA12CYP2A6ENPP1
SCHEMBL19017153 0.76 DYRK1A (0.50) DYRK1ACA2CA12CYP2A6ENPP1
SCHEMBL2824111 0.75 DYRK1A (0.49) DYRK1ACA2CA12CYP2A6
SCHEMBL2825533 0.75 CYP2A6 (0.67) DYRK1ACA2CA12ALDH1A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018093107-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 2018-05-24 WO disclosed