Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 11/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | PDE5A | O76074 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20180396 | 0.84 | ABCG2 (0.33) | SIRT2SIRT1ABCG2ABCB1ABCC1 | |
| SCHEMBL18020247 | 0.80 | ABCG2 (0.50) | SIRT2SIRT1ABCG2ABCB1ABCC1 | |
| SCHEMBL20180559 | 0.78 | MAPT (0.54) | SIRT2SIRT1ABCG2MAPTSMN1; SMN2 | |
| SCHEMBL20180184 | 0.78 | ABCG2 (0.40) | ABCG2ABCB1ABCC1MAPTSMN1; SMN2 | |
| SCHEMBL23561452 | 0.75 | MEN1 (0.58) | ABCG2ABCB1ABCC1MAPTSMN1; SMN2 | |
| SCHEMBL20108954 | 0.75 | ABCG2 (0.49) | ABCG2ABCB1ABCC1MAPTSMN1; SMN2 | |
| SCHEMBL29940289 | 0.74 | MAPT (0.50) | AKR1C3MAPTSMN1; SMN2MEN1TP53 | |
| SCHEMBL881130 | 0.73 | SIRT2 (0.64) | SIRT2SIRT1SYKAKR1C3MAPT | |
| SCHEMBL17720941 | 0.72 | L3MBTL1 (0.56) | MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL19762114 | 0.72 | L3MBTL1 (0.56) | MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093107-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | 주식회사 두산 | 2018-05-24 | — | — | WO | disclosed |