SCHEMBL20180413

SCHEMBL20180413

c1ccc(-c2ccc(-c3cc(-c4cccc(-n5nc(-c6ccccc6)c6ccccc65)c4)nc(-c4ccccc4)n3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
ALDH1A1 P00352 4/20 0.44
MAPT P10636 4/20 0.44
HPGD P15428 3/20 0.44
KDM4E B2RXH2 3/20 0.44
LMNA P02545 2/20 0.44
GLA P06280 1/20 0.44
NTSR1 P30989 1/20 0.42
PTGER1 P34995 4/20 0.41
GAA P10253 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 2/20 0.38
PDE5A O76074 1/20 0.38
RORC P51449 1/20 0.37
ADORA2A P29274 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22214576 0.93 MEN1 (0.44) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL22214572 0.90 ALDH1A1 (0.43) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL22214608 0.86 MEN1 (0.40) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL20180265 0.86 PTGER1 (0.43) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL22214595 0.84 MEN1 (0.43) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL22214598 0.84 MEN1 (0.43) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL22214658 0.83 ALDH1A1 (0.39) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL22214567 0.82 ALDH1A1 (0.43) ALDH1A1MAPTHPGDKDM4ELMNA
SCHEMBL20180256 0.81 PTGER1 (0.38) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL22214548 0.81 MEN1 (0.42) MEN1KMT2AALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018093107-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 2018-05-24 WO disclosed