Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.58 |
| ▸ | TK1 | P04183 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.41 |
| ▸ | TK2 | O00142 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20180389 | 1.00 | DHFR (0.58) | DHFRTK1BCHERNASE1TK2 | |
| SCHEMBL20180386 | 1.00 | DHFR (0.58) | DHFRTK1BCHERNASE1TK2 | |
| SCHEMBL20180392 | 1.00 | DHFR (0.58) | DHFRTK1BCHERNASE1TK2 | |
| SCHEMBL20180391 | 1.00 | DHFR (0.58) | DHFRTK1BCHERNASE1TK2 | |
| SCHEMBL20180384 | 1.00 | DHFR (0.58) | DHFRTK1BCHERNASE1TK2 | |
| SCHEMBL20180462 | 1.00 | DHFR (0.58) | DHFRTK1BCHERNASE1TK2 | |
| SCHEMBL20180461 | 1.00 | DHFR (0.58) | DHFRTK1BCHERNASE1TK2 | |
| SCHEMBL20180532 | 1.00 | DHFR (0.58) | DHFRTK1BCHERNASE1TK2 | |
| SCHEMBL26019454 | 0.92 | DHFR (0.57) | DHFRTK1BCHERNASE1 | |
| SCHEMBL22589436 | 0.82 | DHFR (0.61) | DHFRTK1BCHETK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091542-A1 | CYCLIC PHOSPHATE SUBSTITUTED NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF LIVER DISEASES | IDENIX PHARMACEUTICALS LLC (US) | 2018-05-24 | — | — | WO | disclosed |