Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 20/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21330430 | 0.85 | DGAT2 (0.55) | DGAT2 | |
| SCHEMBL20180358 | 0.85 | DGAT2 (0.65) | DGAT2 | |
| SCHEMBL20180463 | 0.76 | DGAT2 (0.74) | DGAT2 | |
| SCHEMBL20180282 | 0.76 | DGAT2 (0.73) | DGAT2 | |
| SCHEMBL21346795 | 0.76 | DGAT2 (0.66) | DGAT2 | |
| SCHEMBL20166227 | 0.65 | DGAT2 (0.61) | DGAT2 | |
| SCHEMBL31464267 | 0.65 | KDM1A (0.46) | — | |
| SCHEMBL380118 | 0.65 | GLA (0.50) | — | |
| SCHEMBL1558200 | 0.64 | SMYD3 (0.44) | — | |
| SCHEMBL2075337 | 0.64 | KMT2A (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093698-A1 | INDOLE DERIVATIVES USEFUL AS INHIBITORS OF DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 | MERCK SHARP & DOHME CORP. (US) | 2018-05-24 | — | — | WO | disclosed |