Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 7/20 | 0.42 |
| ▸ | CES1 | P23141 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11304466 | 0.92 | CA1 (0.42) | CES2LPAR1LPAR3MEN1KMT2A | |
| SCHEMBL11299245 | 0.92 | CA1 (0.42) | CES2LPAR1LPAR3MEN1KMT2A | |
| SCHEMBL11795301 | 0.82 | CES2 (0.60) | CES2LPAR1LPAR3MEN1KMT2A | |
| SCHEMBL11288151 | 0.82 | CES2 (0.60) | CES2LPAR1LPAR3MEN1KMT2A | |
| SCHEMBL5146085 | 0.82 | CES2 (0.60) | CES2LPAR1LPAR3MEN1KMT2A | |
| SCHEMBL18612495 | 0.82 | MAPT (0.47) | CES2MEN1KMT2AMAPTATM | |
| SCHEMBL28723450 | 0.82 | MAPT (0.47) | CES2MEN1KMT2AMAPTATM | |
| SCHEMBL28070477 | 0.82 | MAPT (0.47) | CES2MEN1KMT2AMAPTATM | |
| SCHEMBL14445397 | 0.82 | MAPT (0.47) | CES2MEN1KMT2AMAPTATM | |
| SCHEMBL28978239 | 0.82 | MAPT (0.47) | CES2MEN1KMT2AMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3151919-B1 | CARBON MONOXIDE-RELEASING MOLECULES FOR THERAPEUTIC APPLICATIONS AND METHODS OF MAKING AND USING THEREOF | UNIV GEORGIA STATE RES FOUND (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2018093924-A1 | CARBON MONOXIDE-RELEASING MOLECULES AND THERAPEUTIC APPLICATIONS THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2018-05-24 | — | — | WO | disclosed |