Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 5/20 | 0.68 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.68 |
| ▸ | OXTR | P30559 | 3/20 | 0.56 |
| ▸ | APLNR | P35414 | 8/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20515259 | 0.84 | AVPR2 (0.54) | AVPR1AAVPR2OXTRAPLNR | |
| SCHEMBL20180784 | 0.84 | APLNR (0.73) | AVPR1AAVPR2OXTRAPLNR | |
| SCHEMBL18254537 | 0.84 | APLNR (0.76) | APLNR | |
| SCHEMBL20180826 | 0.83 | AVPR1A (0.56) | AVPR1AAVPR2OXTRAPLNR | |
| SCHEMBL5832232 | 0.81 | AVPR1A (1.00) | AVPR1AAVPR2OXTR | |
| SCHEMBL18254542 | 0.81 | APLNR (0.54) | AVPR1AAVPR2OXTRAPLNR | |
| SCHEMBL20207289 | 0.81 | APLNR (0.54) | AVPR1AAVPR2OXTRAPLNR | |
| SCHEMBL18254139 | 0.80 | APLNR (0.61) | APLNR | |
| SCHEMBL18254458 | 0.80 | APLNR (0.53) | AVPR1AAVPR2OXTRAPLNR | |
| SCHEMBL22847927 | 0.80 | AVPR1A (0.61) | AVPR1AAVPR2OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093579-A1 | TRIAZOLE PHENYL COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC. (US) | 2018-05-24 | — | — | WO | disclosed |