Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GBA2 | Q9HCG7 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19463532 | 1.00 | CES1 (0.55) | CES1HTTMEN1KMT2ATHRB | |
| SCHEMBL31507409 | 1.00 | CES1 (0.55) | CES1HTTMEN1KMT2ATHRB | |
| SCHEMBL11155708 | 1.00 | CES1 (0.55) | CES1HTTMEN1KMT2ATHRB | |
| SCHEMBL31507425 | 1.00 | CES1 (0.55) | CES1HTTMEN1KMT2ATHRB | |
| SCHEMBL31507420 | 1.00 | CES1 (0.55) | CES1HTTMEN1KMT2ATHRB | |
| SCHEMBL19463378 | 1.00 | CES1 (0.55) | CES1HTTMEN1KMT2ATHRB | |
| SCHEMBL1238411 | 1.00 | CES1 (0.55) | CES1HTTMEN1KMT2ATHRB | |
| SCHEMBL19463076 | 1.00 | CES1 (0.55) | CES1HTTMEN1KMT2ATHRB | |
| SCHEMBL4109335 | 1.00 | CES1 (0.55) | CES1HTTMEN1KMT2ATHRB | |
| SCHEMBL19462935 | 1.00 | CES1 (0.55) | CES1HTTMEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076049-A1 | LIPID COMPOUNDS, LIPID NANOPARTICLES, AND PHARMACEUTICAL COMPOSITIONS | BROADPHARM INC. (US) | 2025-04-10 | — | — | WO | disclosed |
| US-9206230-B2 | Benzylic compound | AJINOMOTO CO., INC. (JP) | 2015-12-08 | — | — | US | disclosed |
| US-9029504-B2 | Fluorene compound | AJINOMOTO CO., INC. (JP) | 2015-05-12 | — | — | US | disclosed |
| US-20140371424-A1 | BENZYLIC COMPOUND | AJINOMOTO CO., INC. (JP) | 2014-12-18 | — | — | US | disclosed |
| US-8859732-B2 | Benzylic compound | AJINOMOTO CO., INC. (JP) | 2014-10-14 | — | — | US | disclosed |
| US-20140046022-A1 | FLUORENE COMPOUND | AJINOMOTO CO., INC. (JP) | 2014-02-13 | — | — | US | disclosed |
| US-8569453-B2 | Fluorene compound | AJINOMOTO CO., INC. (JP) | 2013-10-29 | — | — | US | disclosed |
| EP-2518041-A1 | BENZYL COMPOUND | Ajinomoto Co., Inc. (JP) | 2012-10-31 | — | — | EP | disclosed |
| US-20110160433-A1 | BENZYLIC COMPOUND | AJINOMOTO CO., INC. (JP) | 2011-06-30 | — | — | US | disclosed |
| US-20100240867-A1 | FLUORENE COMPOUND | AJINOMOTO CO. INC. (JP) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160433-A1 | BENZYLIC COMPOUND | VIP, NGLY1, FURIN | CES1 2167/4885HTT 406/4885MEN1 109/4885 |
| US-20140046022-A1 | FLUORENE COMPOUND | NPPA, FURIN, SFPQ | CES1 3863/4885HTT 508/4885MEN1 115/4885 |
| US-20140371424-A1 | BENZYLIC COMPOUND | VIP, NGLY1, FURIN | CES1 2167/4885HTT 406/4885MEN1 109/4885 |
| US-20100240867-A1 | FLUORENE COMPOUND | NPPA, FURIN, SFPQ | CES1 3863/4885HTT 508/4885MEN1 115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.