Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2629371 | 0.74 | APLNR (0.41) | APLNR | |
| SCHEMBL18245652 | 0.72 | APLNR (0.51) | APLNR | |
| SCHEMBL21766947 | 0.72 | APLNR (0.51) | APLNR | |
| SCHEMBL20166817 | 0.72 | APLNR (0.51) | APLNR | |
| SCHEMBL24923750 | 0.71 | APLNR (0.39) | APLNR | |
| SCHEMBL18254626 | 0.71 | APLNR (0.48) | APLNR | |
| SCHEMBL1331897 | 0.71 | APLNR (0.39) | APLNR | |
| SCHEMBL20177680 | 0.71 | APLNR (0.35) | APLNR | |
| SCHEMBL20190471 | 0.68 | APLNR (0.40) | APLNR | |
| SCHEMBL23026166 | 0.67 | APLNR (0.35) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093580-A1 | TRIAZOLE PYRIDYL COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC. (US) | 2018-05-24 | — | — | WO | disclosed |