Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 3/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 16/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 17/20 | 0.56 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8232846 | 0.93 | HDAC3 (0.73) | HDAC2HDAC3KCNH2HDAC1 | |
| SCHEMBL12535755 | 0.89 | HDAC2 (0.60) | HDAC2HDAC3KCNH2HDAC1 | |
| SCHEMBL20181717 | 0.89 | HDAC3 (0.63) | HDAC2HDAC3KCNH2HDAC1 | |
| SCHEMBL15683161 | 0.88 | HDAC1 (0.60) | HDAC2HDAC3KCNH2HDAC1TBK1 | |
| SCHEMBL21538765 | 0.88 | TBK1 (0.60) | HDAC2HDAC3KCNH2HDAC1TBK1 | |
| SCHEMBL15683152 | 0.88 | HDAC1 (0.59) | HDAC2HDAC3KCNH2HDAC1TBK1 | |
| SCHEMBL20163160 | 0.86 | HDAC2 (0.54) | HDAC2HDAC3KCNH2HDAC1TBK1 | |
| SCHEMBL20181514 | 0.86 | HDAC1 (0.56) | HDAC2HDAC3KCNH2HDAC1TBK1 | |
| SCHEMBL20163138 | 0.86 | HDAC2 (0.56) | HDAC2HDAC3KCNH2HDAC1TBK1 | |
| SCHEMBL20181825 | 0.86 | HDAC3 (0.56) | HDAC2HDAC3KCNH2HDAC1TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141923-A1 | SELECTIVE HDAC1,2 INHIBITORS | REGENACY PHARMACEUTICALS, LLC | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141923-A1 | SELECTIVE HDAC1,2 INHIBITORS | HDAC1, HDAC2, HDAC11 | HDAC2 2/4885HDAC3 6/4885KCNH2 4371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.