Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4235557 | 0.88 | ADA (0.39) | SLC6A2PARP1MTNR1AL3MBTL1CYP2C19 | |
| SCHEMBL20181945 | 0.87 | PARP1 (0.41) | SLC6A2PARP1MTNR1AL3MBTL1CYP2C19 | |
| SCHEMBL23940231 | 0.83 | SLC6A2 (0.42) | SLC6A2PARP1MTNR1ASLC2A1L3MBTL1 | |
| SCHEMBL598048 | 0.80 | PARP1 (0.46) | PARP1MTNR1AL3MBTL1CYP2C19CDC7 | |
| SCHEMBL8135638 | 0.77 | PARP1 (0.47) | PARP1MTNR1AL3MBTL1CYP2C19CDC7 | |
| SCHEMBL8134942 | 0.77 | PARP1 (0.44) | PARP1MTNR1AL3MBTL1CYP2C19CDC7 | |
| SCHEMBL25810956 | 0.74 | SLC2A1 (0.46) | SLC29A1BRD4SLC2A1TLR7 | |
| SCHEMBL20037238 | 0.73 | SLC6A2 (0.57) | SLC6A2BRD4SLC2A1HTR2A | |
| SCHEMBL30991276 | 0.73 | PARP1 (0.46) | PARP1MTNR1AL3MBTL1CYP2C19CDC7 | |
| SCHEMBL23938013 | 0.73 | PARP1 (0.46) | PARP1MTNR1AL3MBTL1CYP2C19CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11761007-B2 | Production of unnatural nucleotides using a CRISPR/Cas9 system | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-19 | — | — | US | disclosed |
| US-20200377877-A1 | PRODUCTION OF UNNATURAL NUCLEOTIDES USING A CRISPR/CAS9 SYSTEM | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-12-03 | — | — | US | disclosed |
| WO-2018093968-A1 | IMIDAZOPYRIDAZINE MODULATORS OF IL-12, IL-23 AND/OR IFN-ALPHA | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-24 | — | — | WO | disclosed |